What is Corrositex®?

Corrositex® is a test kit developed by In Vitro International for the purposes of classifying a corrosive substance for skin/dermal corrosion. Corrositex® is a validated OECD in vitro method (OECD 435).

The test can be performed by people with common laboratory bench skills such as weighing and pipetting. See how it’s done in our demonstration video!

The Corrositex® Advantage

  • Accurate hazard classifications and defensible data.
  • A practical alternative to animal testing.
  • For the regulations that apply to your business.
  • Corrositex® (OECD 435) is a fraction of the cost of animal testing.
  • Corrositex® (OECD 435) can reduce shipping costs with properly classified materials.
  • Quick results when the timing is critical.
  • The test can be performed by your staff at your facility.
  • Option to have Dell Tech’s ISO 17025 Accredited lab test your product for you.

Click to download Dell Tech ISO 17025 Certificate & Scope of Accreditation.

Equipment Required to Perform Corrositex®

  • Stirrer hot plate
  • Analytical balance
  • Thermometer
  • Digital Timers (2)
  • Eppendorf repeat pipettor
  • Eppendorf combitips 2.5 mL
  • Suitable container for water bath
  • Refrigerator
  • Plastic wrap

Corrositex® Kit Orders and Inquiries

Please note that Dell Tech distributes Corrositex® Kits in Canada only. For other locations, visit www.invitrointl.com.
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Which Regulations Cite OECD 435 Corrositex® for Testing Skin Corrosion?

 

1. Hazardous Materials Regulations 49CFR173.137

The regulations advise that “for a Class 8 material, the packing group must be determined using data obtained from tests conducted in accordance with the OECD Guideline for the Testing of Chemicals, Number 435, “In Vitro Membrane Barrier Test Method for Skin Corrosion”

2. Transportation of Dangerous Goods (TDG) Regulations Section 2.40

The regulations cite testing is required “as determined in accordance with OECD Guidelines 404 or OECD Guidelines 435;

3. OSHA HCS 2012 Appendix A.2.3

OSHA advises that “In vitro alternatives that have been scientifically validated shall be used to make classification decisions” and “Examples of scientifically validated test methods for skin corrosion include OECD TG…..), and 435 (Membrane Barrier Test Method).

4. Hazards Products Regulations (WHMIS 2015)

Section 8.2.4 includes the use of “…data, in vitro or ex vivo, acquired from a scientifically validated method for the evaluation of skin corrosion” and the Technical guidance on the requirements of the Hazardous Products Act and the Hazardous Products Regulations: WHMIS 2015 supplier requirements. Section 8.2.4 cites “Examples of scientifically validated test methods for Skin Corrosion – Category 1 include…OECD TG 435 – in vitro Membrane Barrier Test Method (e.g., Corrositex®):

5. CPSC Regulations 16CFR1500.41

Includes that the use of “validated in vitro test method is recommended” and the Recommended Procedures Regarding the CPSC’s Policy on Animal Testing offers “Data generated using OECD Guidelines can be considered by CPSC in making a hazard determination as a result of the Mutual Acceptance of Data (MAD) agreement.”

6. Consumer Chemicals and Containers Regulations (CCCR), 2001

CCCR Section 6(1)(e) Precedence of Data Sources accepts “results of tests conducted by the responsible person in accordance with a test methodology that conforms with good scientific practices.” and defines Good Scientific practices as including “test data, conditions and procedures similar to those set out in the OECD Test Guidelines;